Investigation of Betaserc in Auditory and Vestibular Disturbances
Dorina Petrova, Teodora Sachansca, and Emil Datcov
National Transport Hospital, Tzar Boris III, Sofia, Bulgaria
Abstract:
Vestibular vertigo is a primary symptom in neurootological clinical practice and
is common among cerebrovascular diseases. The aim of this investigation was to
evaluate the effect of betahistine dihydrochloride (Betaserc), 8 and 16 mg, on
patients who were transport system workers with vascular auditory and vestibular
disturbances. We examined 50 patients, 30 of whom were treated with 16-mg doses
and 20 of whom received 8-mg doses of Betaserc. The mean age of the patients was
37 ± 2.3 years. The following evaluative methods were used: questionnaire
including detailed neurootological history; ear, nose, and throat and neurological
examinations; tonal threshold audiometry; and examination of the vestibular system
(spontaneous and provoked reactions). On the basis of the investigations carried
out, we recommend 16 mg Betaserc three times daily in the acute phase. The medication
is very well tolerated, has no sedative effect and is suitable for long-term treatment.
Key Words:
Betaserc; electronystagmography; nystagmus; posturography; vascular auditory
and vestibular disturbances