The International Tinnitus Journal

Findings of Nasal Mucosa Cytological Analysis in Integrated Nasal Cavity Disorders

Vokhidov UN, Djuraev JA, Norjigitov FN, Sobirova DR, Jumanov DA, Ismoilov II, Shaumarov AZ, Xakimov IS, Soatov IO

The objective of this study was to examine the cytomorphological characteristics of nasal mucosa smears in patients presenting with combined intranasal structural pathologies. A comprehensive analysis of the cellular composition within the rhinocytogram was performed, evaluating the status of the ciliated epithelium, mucus-secreting cells, inflammatory and immunocompetent cell types, as well as the nature of the microflora. The findings revealed that in this patient population, dystrophic alterations in epithelial cells, moderate hyperplasia of goblet cells, and a neutrophilic inflammatory response were the predominant features. Indicators of a chronic inflammatory process, characterized by compromised mucociliary clearance and persistence of microbial flora, were observed. The results underscore the critical role of combined anatomical and functional abnormalities in the development and sustenance of chronic nasal mucosa pathology, highlighting their practical significance for enhancing diagnostic and therapeutic strategies.