The International Tinnitus Journal

Results of Nasal Mucosa Smear Examination in Patients with Combined Pathologies of the Nasal Cavity and Nasal Valve

Khasanov US, Djuraev JA, Norjigitov FN, Axundjanov NA, Botirov AJ, Rakhimjonova GA, Sultonov DM, Yakubdjanov DD, Mardonov XA

This study aimed to thoroughly assess cytomorphological alterations in nasal mucosa smears from patients with combined nasal and internal nasal valve pathologies. The paper reviews the findings from rhinocytological examinations, covering both quantitative and qualitative analyses of epithelial, inflammatory, and immunocompetent cells, alongside microbial colonization features. It was found that pronounced dystrophic modifications in the ciliated epithelium, hyperplasia of goblet cells, and neutrophilic inflammation are predominant in cases of combined anatomical and functional disorders, signifying a chronic bacterial-associated condition. An increase in degeneratively altered epithelial cells, a high incidence of intracellular microflora, and indications of impaired mucociliary clearance were noted. The findings highlight the crucial role of anatomical narrowing of the nasal valve in sustaining chronic inflammation and persistent nasal obstruction, which is significant for diagnostic and clinical approaches to treatment selection.